Preparation of β-cyclodextrin/polysaccharide foams using saponin

• Max Petitjean and
• José Ramón Isasi

Beilstein J. Org. Chem. 2023, 19, 78–88, doi:10.3762/bjoc.19.7

• polysaccharides. Xanthan gum, locust bean gum or chitosan can be crosslinked using citric acid in the presence of β-cyclodextrin to produce insoluble matrices. In this work, polymeric foams based on those polysaccharides and saponin have been prepared using a green synthesis method to increase the porosity of the

• ; green synthesis; locust bean gum; saponin; sorption; xanthan gum; Introduction Saponins are a family of natural molecules consisting of a hydrophobic aglycone backbone grafted with hydrophilic sugar molecules, allowing the plant to be protected from illnesses [1] and from herbivores endangerment [2

• different polysaccharides (chitosan (CS), locust bean gum (LBG) and xanthan gum (XG)) were tested either by themselves or mixed in a 50:50 ratio with β-cyclodextrin. A fast emergence of the liquid fraction occurred with the solution containing cyclodextrin with no polysaccharides. These results show that

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

• Luke O. Jones,
• Leah Williams,
• Tasmin Boam,
• Martin Kalmet,
• Chidubem Oguike and
• Fiona L. Hatton

Beilstein J. Org. Chem. 2021, 17, 2553–2569, doi:10.3762/bjoc.17.171

• proliferation. Chitosan has also been used by Meena et al. for producing cryogels for haemostatic applications, with locust bean gum (LBG) incorporated to enhance mechanical properties and water absorption [32]. This chitosan/LBG semi-interpenetrating network cryogel was investigated for its swelling

Synthetic and semi-synthetic approaches to unprotected N-glycan oxazolines

• Antony J. Fairbanks

Beilstein J. Org. Chem. 2018, 14, 416–429, doi:10.3762/bjoc.14.30

• synthetic approaches reported, the majority rely on the fabrication (either by total synthesis, or semi-synthesis from locust bean gum) of a key Manβ(1–4)GlcNAc disaccharide, which can then be elaborated at the 3- and 6-positions of the mannose unit using standard glycosylation chemistry. Early approaches

• in the presence of Et3N resulted in conversion to the glycosyl oxazoline in an excellent 95% yield. Semi-synthesis: the locust bean gum approach The naturally occurring polysaccharide locust bean gum contains a repeating Manβ(1–4)Man disaccharide unit, which is also decorated with branching α

• -galactose residues attached to OH-6 of some of the mannoses. Nishimura and co-workers [81] realised the potential utility of this Manβ(1–4)Man disaccharide in an expedient route to the part of N-glycans that is most difficult to synthesise; namely the Manβ(1–4)GlcNAc linkage. Treatment of locust bean gum

Stability of SG1 nitroxide towards unprotected sugar and lithium salts: a preamble to cellulose modification by nitroxide-mediated graft polymerization

• Guillaume Moreira,
• Laurence Charles,
• Mohamed Major,
• Florence Vacandio,
• Yohann Guillaneuf,
• Catherine Lefay and
• Didier Gigmes

Beilstein J. Org. Chem. 2013, 9, 1589–1600, doi:10.3762/bjoc.9.181

• locust bean gum, cellulose is not soluble in water and hardly soluble in few organic media. Consequently, its modification by polymer grafting proceeds either in organic media under homogeneous conditions or under heterogeneous conditions (surface-initiated polymerization from cellulose fibre, pulp